All About Positive Health

• Tags

  abscess Add new tag Antibiotic Asia atherosclerosis Bacteria Bleeding Blog Blood vessel Breast Cancer Cardiovascular Disorders Circumcision Cirrhosis Conditions and Diseases Death Diabetes Diabetes mellitus Digestive Disorders Esophagus Gallbladder God Government Health Heart disease Hospital Hypertension Immunization India Infection Infectious disease Liver Medicine Musculoskeletal Disorders myocardial infarction Orissa Peptic ulcer rabies Rectum Stomach Surgery Tendon Tobacco Vaccine Virus

• From A clinician’s Bioscope

  • Links for 2012-01-31 [Digg] February 1, 2012
    Bedsores can be Responsible for Considerable Morbidity and Mortality Bedsores can kill almost as many as the hospital superbug MRSA (Methicillin Resistant Staphylococcus Aureus) and cost a lot to the exchequer anywhere in the world. Even when they don’t kill, they inflict terrible pain, discomfort; and rob the sufferer of their time and money. Read more; htt […]
  • Links for 2012-01-30 [Digg] January 31, 2012
    Melatonin and Risk of Developing Diabetes Mellitus In addition to inducing sleep, it also acts on different organs of body and influence their functions too. So it regulates the “biological clock” responsible for sleep/wake pattern. It has been seen that people engaged in night shift duty are prone to develop type II diabetes (DM Type II) mellitus, obesity a […]
  • Melatonin and Risk of Developing Diabetes Mellitus January 30, 2012
    Melatonin is a hormone secreted from pineal gland located in the under surface of brain. Its’ secretion is influenced by light and dark; dark inducing its release. Image via Wikipedia;... [[ This is a content summary only. Visit my website for full links, other content, and more! ]] […]

• Archives

  Select Month January 2012  (1) October 2011  (1) April 2011  (14) February 2011  (1) January 2011  (1) September 2010  (2) August 2010  (3) July 2010  (4) June 2010  (3) May 2010  (1) April 2010  (7) March 2010  (4) February 2010  (2) January 2010  (6) December 2009  (7) November 2009  (7) October 2009  (12) September 2009  (21) August 2009  (24) July 2009  (30) June 2009  (24) May 2009  (22) April 2009  (28) March 2009  (31) February 2009  (4)

• Recent Posts

  • New Year 2012
  • burning brown fat by Orexin Hormone to Tackle Obesity
  • Auto Post 04/27/2011
  • Auto Post 04/26/2011
  • Auto Post 04/25/2011
  • Auto Post 04/24/2011
  • Auto Post 04/23/2011
  • Auto Post 04/22/2011
  • Auto Post 04/20/2011
  • Auto Post 04/19/2011

• ClinicianOnNet

  • Links for 2012-01-31 [Digg] February 1, 2012
    Bedsores can be Responsible for Considerable Morbidity and Mortality Bedsores can kill almost as many as the hospital superbug MRSA (Methicillin Resistant Staphylococcus Aureus) and cost a lot to the exchequer anywhere in the world. Even when they don’t kill, they inflict terrible pain, discomfort; and rob the sufferer of their time and money. Read more; htt […]
  • Bedsores can be Responsible for Considerable Morbidity and Mortality January 31, 2012
    Bedsores can kill almost as many as the hospital superbug MRSA (Methicillin Resistant Staphylococcus Aureus) and cost a lot to the exchequer anywhere in the world. Even when they don’t kill, they... [[ This is a content summary only. Visit my website for full links, other content, and more! ]] […]
  • Links for 2012-01-30 [Digg] January 31, 2012
    Melatonin and Risk of Developing Diabetes Mellitus In addition to inducing sleep, it also acts on different organs of body and influence their functions too. So it regulates the “biological clock” responsible for sleep/wake pattern. It has been seen that people engaged in night shift duty are prone to develop type II diabetes (DM Type II) mellitus, obesity a […]

• Get it Delivered to YOU.

  Enter your email address:

  Delivered by FeedBurner

• Recent Comments

  • Houston Texas Gastroenterologist on G.I. ENDOSCOPY.
  • get likes on About
  • Ringia on About

• Meta

  • Register
  • Log in
• 
  

  0	Unique Visitors

  Powered By

• Pages

  • About

• Recently Active Member Avatars

  

  

  

  

  

DNA Repair in Mice with BRCA1 Gene Mutations

Posted by Dr.Prahallad Panda on April 6, 2010

Share

It may be possible in the near future that researchers will be able to identify all those factors those play their role in transforming normal cells to abnormal; initiating and sustaining uncontrolled growth, and rendering them resistant to treatment.

clipped from www.cancer.gov Scientists Restore DNA Repair in Mice with BRCA1 Gene Mutations The gene BRCA1 plays an important role in repairing DNA damage that inevitably occurs as cells replicate. Through a pathway known as homologous recombination (HR), the gene helps cells make repairs and prevent further genetic changes that could set the stage for cancer. But as a new study in mice suggests, multiple pathways may actually compete with one another to repair DNA damage within cells. The study further suggests that it may be possible to restore the HR pathway and promote faithful DNA repair in cells with BRCA1 mutations. An enzyme called DNA ligase repairs a broken strand of DNA. (Image courtesy of Dr. Tom Ellenberger, Washington University School of Medicine in St. Louis.) Some repair pathways, he noted, do more harm than good. While the HR pathway is essentially free of errors, the 53BP1-associated pathway produces genetic mutations that increase the risk of cancer when the BRCA1 protein is absent.

This entry was posted on April 6, 2010 at 6:43 pm and is filed under Uncategorized. . You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

Leave a Reply