All About Positive Health

• Tags

  abscess Add new tag Antibiotic Asia atherosclerosis Bacteria Bleeding Blog Blood vessel Breast Cancer Cardiovascular Disorders Circumcision Cirrhosis Conditions and Diseases Death Diabetes Diabetes mellitus Digestive Disorders Esophagus Gallbladder God Government Health Heart disease Hospital Hypertension Immunization India Infection Infectious disease Liver Medicine Musculoskeletal Disorders myocardial infarction Orissa Peptic ulcer rabies Rectum Stomach Surgery Tendon Tobacco Vaccine Virus

• From A clinician’s Bioscope

  • Links for 2012-01-31 [Digg] February 1, 2012
    Bedsores can be Responsible for Considerable Morbidity and Mortality Bedsores can kill almost as many as the hospital superbug MRSA (Methicillin Resistant Staphylococcus Aureus) and cost a lot to the exchequer anywhere in the world. Even when they don’t kill, they inflict terrible pain, discomfort; and rob the sufferer of their time and money. Read more; htt […]
  • Links for 2012-01-30 [Digg] January 31, 2012
    Melatonin and Risk of Developing Diabetes Mellitus In addition to inducing sleep, it also acts on different organs of body and influence their functions too. So it regulates the “biological clock” responsible for sleep/wake pattern. It has been seen that people engaged in night shift duty are prone to develop type II diabetes (DM Type II) mellitus, obesity a […]
  • Melatonin and Risk of Developing Diabetes Mellitus January 30, 2012
    Melatonin is a hormone secreted from pineal gland located in the under surface of brain. Its’ secretion is influenced by light and dark; dark inducing its release. Image via Wikipedia;... [[ This is a content summary only. Visit my website for full links, other content, and more! ]] […]

• Archives

  Select Month January 2012  (1) October 2011  (1) April 2011  (14) February 2011  (1) January 2011  (1) September 2010  (2) August 2010  (3) July 2010  (4) June 2010  (3) May 2010  (1) April 2010  (7) March 2010  (4) February 2010  (2) January 2010  (6) December 2009  (7) November 2009  (7) October 2009  (12) September 2009  (21) August 2009  (24) July 2009  (30) June 2009  (24) May 2009  (22) April 2009  (28) March 2009  (31) February 2009  (4)

• Recent Posts

  • New Year 2012
  • burning brown fat by Orexin Hormone to Tackle Obesity
  • Auto Post 04/27/2011
  • Auto Post 04/26/2011
  • Auto Post 04/25/2011
  • Auto Post 04/24/2011
  • Auto Post 04/23/2011
  • Auto Post 04/22/2011
  • Auto Post 04/20/2011
  • Auto Post 04/19/2011

• ClinicianOnNet

  • Links for 2012-01-31 [Digg] February 1, 2012
    Bedsores can be Responsible for Considerable Morbidity and Mortality Bedsores can kill almost as many as the hospital superbug MRSA (Methicillin Resistant Staphylococcus Aureus) and cost a lot to the exchequer anywhere in the world. Even when they don’t kill, they inflict terrible pain, discomfort; and rob the sufferer of their time and money. Read more; htt […]
  • Bedsores can be Responsible for Considerable Morbidity and Mortality January 31, 2012
    Bedsores can kill almost as many as the hospital superbug MRSA (Methicillin Resistant Staphylococcus Aureus) and cost a lot to the exchequer anywhere in the world. Even when they don’t kill, they... [[ This is a content summary only. Visit my website for full links, other content, and more! ]] […]
  • Links for 2012-01-30 [Digg] January 31, 2012
    Melatonin and Risk of Developing Diabetes Mellitus In addition to inducing sleep, it also acts on different organs of body and influence their functions too. So it regulates the “biological clock” responsible for sleep/wake pattern. It has been seen that people engaged in night shift duty are prone to develop type II diabetes (DM Type II) mellitus, obesity a […]

• Get it Delivered to YOU.

  Enter your email address:

  Delivered by FeedBurner

• Recent Comments

  • Houston Texas Gastroenterologist on G.I. ENDOSCOPY.
  • get likes on About
  • Ringia on About

• Meta

  • Register
  • Log in
• 
  

  0	Unique Visitors

  Powered By

• Pages

  • About

• Recently Active Member Avatars

  

  

  

  

  

Metformin Associated Vitamin B Defficiency

Posted by Dr.Prahallad Panda on May 22, 2010

Share

The researchers have found out that metformin a medication for obesity and diabetes may cause vitamin B 12 deficiency.

clipped from www.medpagetoday.com Keeping Tabs on Vitamin B Advised with Metformin The association of metformin treatment with vitamin B12 deficiency was confirmed in a long-term trial, suggesting that diabetic patients receiving the popular drug would benefit from vitamin monitoring and perhaps B12 supplementation. With 4.3 years of treatment in a randomized, placebo-controlled trial, the hazard ratio for developing vitamin B12 deficiency while on metformin was 5.5 relative to placebo (95% CI 1.6 to 19.1), reported Coen Stehouwer, MD, of Maastricht University in the Netherlands, and colleagues online in BMJ. “Our study shows that this decrease is not a transitory phenomenon, but persists and grows over time,” the researchers wrote. From a mean of about 355 pmol/L at the end of the run-in phase, B12 levels dropped to about 305 pmol/L after four months, and from there to 280 pmol/L over the next four years.

This entry was posted on May 22, 2010 at 6:41 am and is filed under Uncategorized. . You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

2 Responses to “Metformin Associated Vitamin B Defficiency”

1.   Jillian@Moringa Says:
   May 16th, 2011 at 1:49 pm

   Do you know if metformin has any side effects? I’ve become really sceptical over the years – I don’t want to damage my body!

2.   Dr.Prahallad Panda Says:
   May 16th, 2011 at 6:34 pm

   Dear,
   Every drug has some adverse reaction. Metformin is rather a safe drug. One may have GI upset and headache. To minimize it, your doctor will guide you. It is good to start from lower doses and in sustained release form.

Leave a Reply