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Synthesis of Natural Joint

Posted by Dr.Prahallad Panda on July 29, 2010

Bone was made outside the body, so also flesh. Now it is joint. If, it finally comes to the clinicians, it will be a boon.
clipped from timesofindia.indiatimes.com
A natural replacement for worn-out joint


PARIS: Scientists have shown for the
first time that it may be possible to replace a human hip or knee with a joint
grown naturally inside the body using the patient’s stem cells.

In
experiments on rabbits, the researchers coaxed the animals’ stem cells to
rebuild the bone and cartilage of a missing leg joint, according to a study
published on Thursday. “This is the first time an entire joint surface was
regenerated with return of functions including weight-bearing and locomotion,”
lead researcher Jeremy Mao, a professor at Columbia University Medical Center,
said.

In the
experiments, Mao and colleagues removed the forelimb thigh joint of 10 rabbits,
and then implanted a kind of scaffolding made of biologically compatible
materials.

The
fact that the regenerated limb joint was created from the stem cells in the host
animal — rather than being harvested and then cultivated outside the body
— is also unprecedented, they said.
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