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  • Links for 2012-03-28 [Digg] March 29, 2012
    Bleeding During Catheterization of Male Urethra I was called at 10.30 PM to attend a case of bleeding from urethra following urethral catheterization in a semiconscious male, admitted to the medicine ward. I went and saw a healthy male in sixties bleeding from urethra. The foley's catheter, a narrow silicon tube used for draining the retained urine was […]
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    A Common Blood Pressure Lowering Drug Verapamil may Slow Or Reverse Diabetes A common medication for high-blood-pressure and angina, verapamil, a calcium channel blocker has been seen to protect or reverse diabetes-related death of pancreatic beta cells, those responsible for secretion of insulin; according to a University of Alabama at Birmingham study publ […]
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Lipid Regulating Gene Number Goes Up

Posted by Dr.Prahallad Panda on August 5, 2010

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Control of LDL, the bad cholesterol can now be targeted a a better way; it is hoped.

clipped from www.medpagetoday.com New Gene Variants Linked to Lipid Levels In a genetic analysis of more than 100,000 people of European ancestry, researchers have found 95 common genetic variants — 59 of them previously unknown — that influence lipid levels by regulating nearby genes. And at least one actually causes increases in low-density lipoprotein cholesterol (LDL-C) by decreasing the expression in the liver of a gene called Sort1. The gene lies in a region previously linked to about a 40% increase in the risk of heart attack, but the mechanism has not been understood. That target may not be the gene product of Sort1 — a protein dubbed sortilin — according to Kathiresan. But the study “exposes basically a new pathway, a new way of regulating lipids, LDL cholesterol, that’s actually independent of or different than previous approaches,” he said.

This entry was posted on August 5, 2010 at 9:03 am and is filed under Uncategorized. . You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

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